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KMID : 1143420180110361197
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Public Health Weekly Report
2018 Volume.11 No. 36 p.1197 ~ p.1199
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Epidemiologic investigation and the follow-up result for unexplained respiratory illness in a university laboratory
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Chun Byung-Chul
Yoo Kwang-Ha
Kim Eun-Kyoung
Choi Eun-Kyoung
Moon Sang-Jun
Lee Sang-Won
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Abstract
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In 2015, an unexplained respiratory illness occurred in a university laboratory. As a result, an epidemiologic investigation
was conducted by the Korea Centers for Disease Control and Prevention (KCDC) and civilian experts. The epidemiologic
investigation led us to suggest that the unexplained respiratory illness is likely to be organic dust toxic syndrome (ODTS)
caused by endotoxin, etc., in the feeds. Patients with symptoms showed a rapid clinical progression and no possibility of
human-to-human transmission. Symptomatic cases were followed up with low-dose chest computed tomography (CT) after discharge (totaling 4 times) according to expert opinion. Although follow-up CT scans showed that cases had remained single or as multiple small nodules, the overall size and number of lesions showed a decease, indicating that additional follow-up observations for the remaining lesions may be unnecessary.
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KEYWORD
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Unexplained respiratory illness, Epidemiologic investigation, Organic dust toxic syndrome (ODTS)
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